Results 41 to 50 of about 245,755 (295)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Preparation and infrared stealth properties of SiO2/Al2O3 nanocomposite powders with low emissivity

open access: yes工程科学学报, 2016
Crystalline and amorphous SiO2/Al2O3 nanocomposite powders were prepared by a sol-gel method. The structure and morphology of the nanocomposite powders were characterized by X-ray diffraction and transmission electron microscopy, while the in-frared ...
CHEN Ke   +4 more
doaj   +1 more source

Investigation of the Influence of the Mixing Process on the Powder Characteristics for Cyclic Reuse in Selective Laser Sintering

open access: yesPowders, 2023
Selective laser sintering (SLS) with polymers is currently at the transition to the production of functional components and thus holds great potential to revolutionize conventional production processes.
Tom Eggers   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Nanocrystalline apatites: From powders to biomaterials [PDF]

open access: yes, 2009
Non-stoichiometric nanocrystalline apatite powders are used to elaborate highly-bioactive biomaterials. Their exceptional surface reactivity arises from a structured but rather unstable hydrated layer involving ions in nonapatitic chemical environments ...
Estournès, Claude   +8 more
core   +1 more source

Effect of Particle Size on Physical Properties, Dissolution, In Vitro Antioxidant Activity, and In Vivo Hepatoprotective Properties of Tetrastigma hemsleyanum Diels et Gilg Powders

open access: yesPharmaceutics
Objective: The aim of this study was to analyze the effects of different particle sizes of Tetrastigma hemsleyanum Diels et Gilg (TDG) powders on physical properties, dissolution, in vitro antioxidant activity, and in vivo hepatoprotective properties ...
Zhiwen Zhang   +9 more
doaj   +1 more source

Elucidating Powder-Mixed Electric Discharge Machining Process, Applicability, Trends and Futuristic Perspectives

open access: yesMachines, 2023
Since the inception of electric discharge machining (EDM), it has facilitated the production industries, for instance, die & mold, automotive, aerospace, etc., by providing an effective solution for machining hard-to-cut materials and intricate ...
Iqtidar Ahmed Gul   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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