A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu +6 more
wiley +1 more source
Examining the Mediating Role of Psychological Resilience in the Relationship Between Religious Coping and Menopausal Symptoms. [PDF]
Çakmak FS, Varışoğlu YY, Aslan M.
europepmc +1 more source
Research progress on biomarkers of traumatic brain injury
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source
Predicting Theta/Alpha Neurofeedback Success through Psychological and Personality Profiles: A Hybrid Approach Using Multilayer Perceptron and Elastic Net Models. [PDF]
Hasheminia S, Sho'ouri N, Mahmoudi MT.
europepmc +1 more source
Lung maneuvers of large amplitudes for probing physiological alterations in mouse models of asthma
Lung maneuvers of small amplitudes, such as the ones performed in oscillometry, are the current gold standard to probe lung mechanics in animals, but they are insensitive to detect baseline physiological alterations in mouse models of asthma. Herein, lung maneuvers of different amplitudes were compared in two mouse models of asthma.
Magali Boucher +4 more
wiley +1 more source
"Imposed Motherhood, Interrupted Childhood": child marriage, postpartum trauma, and the failure of SDG commitments in Chennai's inner city. [PDF]
Priyadharshini J, Karthiga RKJ.
europepmc +1 more source
We applied quantitative MRI of the lower limb and automated home‐cage phenotyping to a mouse model of calpainopathy to detect early disease changes. At 15 months, calpain 3‐deficient mice showed increased water T2 values correlating with immune cell infiltration in the soleus and gastrocnemius muscles, while assessment of motor activity revealed only ...
Nicolina Südkamp +12 more
wiley +1 more source
Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova +27 more
wiley +1 more source
Does Cardiorespiratory Fitness Predict the Physiological and Psychological Stress Response to a Mathematics Exam in Secondary High School Students? [PDF]
Gerber M, Haller M, Looser VN, Ludyga S.
europepmc +1 more source
Objective The objective of this study was to examine whether machine learning has the capacity to prospectively identify and predict the emergence of Fragile X‐associated tremor/ataxia syndrome (FXTAS) among male fragile X premutation carriers (PCs). Methods We explored neuropsychological and motor evaluation metrics, brain magnetic resonance imaging ...
Chitrabhanu Gupta +10 more
wiley +1 more source

