Results 51 to 60 of about 65,434,810 (316)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimal Bidding Capacity of Virtual Power Plant Incorporating Power-to-X Resources on Day-Ahead Energy Market

Energies
Sector coupling technology, which is also called power-to-X (P2X) technology, refers to the conversion of renewable energy system (RES) outputs into various forms of energy, enhancing the utility of RESs and facilitating the development of sustainable ...
Kyeong-Hee Cho, Hyung-Chul Jo, Wanbin Son, Soon-Young Kwon, Gilsung Byeon   +4 more
doaj   +1 more source

A Review on Synthesis of Methane as a Pathway for Renewable Energy Storage With a Focus on Solid Oxide Electrolytic Cell-Based Processes

Frontiers in Energy Research, 2020
Environmental issues related to global warming are constantly pushing the fossil fuel-based energy sector toward an efficient and economically viable utilization of renewable energy.
Saheli Biswas, Aniruddha P. Kulkarni, Sarbjit Giddey, Sankar Bhattacharya   +3 more
doaj   +1 more source

Power-to-X / electricity-to-hydrogen in sector coupling: an overview & case studies

Renewable Energy and Sustainable Development, 2021
During the past couple of years, Power-to-X-to-Power has been a research and development focal point within the field of renewable energy - with thermal energy storage (TES) as an essential part of the concept.
Hammam Abdelaal Hammam Soliman, Peter Badstue Jensen   +1 more
doaj   +1 more source

Improved system operations with high penetration of wind power : a dialog between academia and industry - Ireland

, 2010
Panel session submission for the IEEE Power and Energy Society (PES) 2010 General Meeting, July 25-29 2010, Minneapolis, MinnesotaThis is a submission to a panel session at the 2010 IEEE PES General Meeting. It discusses effective collaboration between
Power, Michael, Michael Power, O\u27Malley, Mark, O'Malley, Mark, Mark O'Malley   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Impact of wind power on the unit commitment, operating reserves and market design

, 2011
Paper presented at the 2011 IEEE Power and Energy Society General Meeting, San Diego, CA, 24-29 July 2011This article highlights and demonstrates the new requirements variable and partly unpredictable wind power will bring to unit commitment and power ...
Milligan, M., Lange, B., Gibescu, M., Michael Milligan, Hannele Holttinen, Lange, Bernard, Kiviluoma, K., Juha Kiviluoma, Meibom, P., Meibom, Peter, O\u27Malley, Mark, Peter Meibom, Madeleine Gibescu, Kiviluoma, Juha; id_orcid, Tuohy, Aidan, Holttinen, H., Tuohy, A., Gibescu, Madeleine, Holttinen, Hannele, O'Malley, M., Milligan, Michael R., Bernhard Lange, Kiviluoma, Juha, Aidan Tuohy, O'Malley, Mark, Mark O'Malley   +25 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Perturbative corrections to power suppressed effects in B ¯ $$ \overline{B} $$ → X u ℓν

Journal of High Energy Physics, 2021
We compute the O(α s ) corrections to the Wilson coefficients of the dimension five operators in inclusive semileptonic B decays in the limit of a massless final quark.
Bernat Capdevila, Paolo Gambino, Soumitra Nandi   +2 more
doaj   +1 more source