Results 41 to 50 of about 1,292,199 (328)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

CNN-Based End-to-End CPU-AP-UE Power Allocation for Spectral Efficiency Enhancement in Cell-Free Massive MIMO Networks

Mathematics
Cell-free massive multiple-input multiple-output (MIMO) networks eliminate cell boundaries and enhance uniform quality of service by enabling cooperative transmission among access points (APs). In conventional cellular networks, user equipment located at
Yoon-Ju Choi, Ji-Hee Yu, Seung-Hwan Seo, Seong-Gyun Choi, Hye-Yoon Jeong, Ja-Eun Kim, Myung-Sun Baek, Young-Hwan You, Hyoung-Kyu Song   +8 more
doaj   +1 more source

5G green cellular networks considering power allocation schemes

, 2015
It is important to assess the effect of transmit power allocation schemes on the energy consumption on random cellular networks. The energy efficiency of 5G green cellular networks with average and water-filling power allocation schemes is studied in ...
Chen, Jiaqi, Ge, Xiaohu, Thompson, John, Wang, Cheng-xiang, Zhang, Jing   +4 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Spatial and temporal evolution trends of groundwater drought and its correlation with meteorological drought in Guizhou province

Agricultural Water Management
Groundwater constitutes a vital water resource in karst regions, where conventional surface-based drought indicators frequently fail to accurately capture groundwater deficits. However, the applicability of GRACE satellite data for monitoring groundwater
Aili Wang, Yuanxiao Xing, Shunsheng Wang, Donglin Wang, Cundong Xu   +4 more
doaj   +1 more source

A Hierarchical Framework of Cloud Resource Allocation and Power Management Using Deep Reinforcement Learning

, 2017
Automatic decision-making approaches, such as reinforcement learning (RL), have been applied to (partially) solve the resource allocation problem adaptively in the cloud computing system.
Li, Zhe, Lin, Sheng, Liu, Ning, Qiu, Qinru, Tang, Jian, Wang, Yanzhi, Xu, Jielong, Xu, Zhiyuan   +7 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Hydrological drought dynamic using copula functions and drought center migration in the Ganjiang river basin

Scientific Reports
Understanding the spatiotemporal evolution of hydrological drought is essential for effective drought management. This study investigated hydrological drought in Ganjiang River Basin (GRB), China from 1959 to 2019 using observed and SWAT-simulated runoff
Weilin Liu, Jingrong Zhang, Zhanxiong Zhou, Shengnan Zhu, Lina Liu, Jianzhu Li   +5 more
doaj   +1 more source

Research on power fluctuation strategy of hybrid energy storage to suppress wind-photovoltaic hybrid power system

Energy Reports, 2023
In this paper, an adaptive hybrid energy storage power optimal allocation strategy is proposed. The strategy aims to suppress the fluctuation of grid-connected power under different operation conditions and improve the operation reliability of a high ...
Lin Zhang, Tianwen Zhang, Ke Zhang, Wenbo Hu   +3 more
doaj   +1 more source

Cooperative Interference Control for Spectrum Sharing in OFDMA Cellular Systems

, 2011
This paper studies cooperative schemes for the inter-cell interference control in orthogonal-frequency-divisionmultiple- access (OFDMA) cellular systems.
Da, Bin, Zhang, Rui
core   +1 more source