Results 71 to 80 of about 2,254,969 (255)

Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling

Stem Cell Reports, 2017
Both the promises and pitfalls of the cell reprogramming research platform rest on human genetic variation, making the measurement of its impact one of the most urgent issues in the field.
Pierre-Luc Germain, Giuseppe Testa
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

A General Framework for Planning the Number of Items/Subjects for Evaluating Cronbach’s Alpha: Integration of Hypothesis Testing and Confidence Intervals

Methodology
Cronbach’s alpha, widely used for measuring reliability, often operates within studies with sample information, suffering insufficient sample sizes to have sufficient statistical power or precise estimation.
Wei-Ming Luh
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

HETEROGENEITY AND POWER TO DETECT TRENDS IN MOOSE BROWSE UTILIZATION OF WILLOW COMMUNITIES

Alces, 2017
Monitoring of browse utilization of plant communities is consistently recommended as an important component of monitoring moose (Alces alces) populations across regions.
Braden O. Burkholder, Nicholas J. DeCesare, Robert A. Garrott, Sylvanna J. Boccadori   +3 more
doaj  

Hybrid Power System Power Flow Analysis

Energy and Power Engineering, 2013
Hybrid power supply system consists of a number of independent and different sources of electrical energy with different operating times during different seasons and with energy storage system. Deployment of a hybrid power system is expected in places outside the normal distribution network.
Petr Bilik, Jakub Manas, Jan Zidek, Jiri Koziorek   +3 more
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

SM9‑based CP‑ABE Access Control Scheme under Power IoT

Taiyuan Ligong Daxue xuebao
[Purposes] This work has been carried out to achieve fine-grained access control based on the existing power IoT. [Methods] A ciphertext policy attribute based encryption (CPABE) scheme for power IoT scenarios based on the SM9 algorithm was proposed ...
ZHANG Yanjie, WANG Hui, LI Yan, ZHANG Xing, ZHANG Liang, YUAN Yanfang, SHI Zhentong   +6 more
doaj   +1 more source

A framework for power analysis using a structural equation modelling procedure

BMC Medical Research Methodology, 2003
Background This paper demonstrates how structural equation modelling (SEM) can be used as a tool to aid in carrying out power analyses. For many complex multivariate designs that are increasingly being employed, power analyses can be difficult to carry ...
Miles Jeremy
doaj   +1 more source