Results 81 to 90 of about 9,414,122 (340)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cascading Failures in Power Grids - Analysis and Algorithms [PDF]

open access: yes, 2014
This paper focuses on cascading line failures in the transmission system of the power grid. Recent large-scale power outages demonstrated the limitations of percolation- and epid- emic-based tools in modeling cascades.
Dorian Mazauric   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling

open access: yesStem Cell Reports, 2017
Both the promises and pitfalls of the cell reprogramming research platform rest on human genetic variation, making the measurement of its impact one of the most urgent issues in the field.
Pierre-Luc Germain, Giuseppe Testa
doaj   +1 more source

Analysis of large power systems [PDF]

open access: yes
Computer-oriented power systems analysis procedures in the electric utilities are surveyed. The growth of electric power systems is discussed along with the solution of sparse network equations, power flow, and stability ...
Dommel, H. W.
core   +1 more source

Features in the primordial power spectrum? A frequentist analysis

open access: yes, 2010
Features in the primordial power spectrum have been suggested as an explanation for glitches in the angular power spectrum of temperature anisotropies measured by the WMAP satellite.
Hamann, Jan   +2 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DEAとInverted DEAのノンパラメトリック検定を用いたわが国の電力各社の生産性に対する電力自由化の効果検証 [PDF]

open access: yes, 2018
This paper is verifying of the effects on the electric power deregulation in Japan to the productivity of each electric power company by using the parametric and nonparametric test of the DEA (Data Envelopment Analysis) and the Inverted DEA (Inverted ...
SUGIYAMA, Manabu   +2 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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