Results 141 to 150 of about 670,349 (316)

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Improvement of the Aerodynamic Performance of a Darrieus Vertical-Axis Wind Turbine Using a Passive Deflector in Urban Environments

Energies
The integration of wind energy into urban environments is constrained by low wind speeds, high turbulence, and the recurrent negative torque experienced by lift-driven vertical-axis wind turbines (VAWTs).
Beatriz Salvador-Gutierrez, Lozano Sanchez-Cortez, Lincold Dante-Salvatierra, Guillermo Casanova-Gonzalez, Jorge Montaño-Pisfil, Roberto Solis-Farfan, Alex Vallejos-Zuta, Cesar Santos-Mejia, Gabriel Tirado-Mendoza, Jose Poma-Garcia, Oswaldo Casazola-Cruz, Olger Ortega-Achata   +11 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

A Single-Transmitter Multi-Receiver Wireless Power Transfer System with High Coil Misalignment Tolerance and Variable Power Allocation Ratios

This article proposes a single-transmitter multi-receiver wireless power transfer (STMR-WPT) system, which uses a cross-overlapped bipolar coil as the transmitter and multiple square unipolar coils as the receivers.
Zhuoyue Dai, Yongmin Yang, Yanting Luo
core   +1 more source

Energy optimization through morphing blade design under structural constraints: a case study on the NREL 1.5 MW wind turbine

Science and Technology for Energy Transition
This study explores a novel morphing blade design methodology to enhance the aerodynamic performance of the NREL 1.5 MW wind turbine while addressing structural constraints.
Najafian Arezoo, Jahangirian Alireza
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Full-Scale Experimental Assessment of a Horizontal-Axis Hydrokinetic Turbine for River Applications: A Challenge for Developing Countries

Energies
This paper presents an experimental investigation into the performance of a horizontal-axis turbine deployed in the Sinú River. The primary objective is to assess the turbine’s functionality under actual water flow conditions.
Edwin Chica, Laura Velásquez, Ainhoa Rubio-Clemente   +2 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Incorporating Cost in Power Analysis for Three-Level Cluster Randomized Designs [PDF]

In experimental designs with nested structures entire groups (such as schools) are often assigned to treatment conditions. Key aspects of the design in these cluster randomized experiments include knowledge of the intraclass correlation structure and the
Konstantopoulos, Spyros
core  

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source