Results 51 to 60 of about 1,133,853 (295)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Role of membrane potential fluctuations to the criticality of neuronal avalanche activity [PDF]
Experimental evidence for self-organised criticality (SOC) in non-conservative systems has recently been found in studies of rat cortical slices. The size distribution of observed neuronal avalanches has been attested to obey $3/2$ power-law scaling.
Juanico, Dr Dranreb Earl
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
With the increasing scale of new energy, flexible DC, FACTS and other new power electronic equipment connecting to the power grid, the operational characteristics of the new large-scale power grid have undergone significant changes, and electromagnetic ...
Shuwen XU +4 more
doaj +1 more source
Symmetries and Symmetry Breaking
In understanding the world of matter, the introduction of symmetry principles following experimentation or using the predictive power of symmetry principles to guide experimentation is most profound.
Berdoz +12 more
core +2 more sources
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Synchronization Stability Analysis of PLL-Based Grid-Connected VSC System by Voltage Space Vectors
This paper focuses on synchronization stability analysis of the power system, in which power electronics are synchronized by the phase-locked loop (PLL).
Huadong Sun +4 more
doaj +1 more source
An online line switching methodology to relieve voltage violations is proposed. This novel online methodology is based on a three-stage strategy, including screening, ranking, and detailed analysis and assessment stages for high speed (online application)
Zhengwei Shen +5 more
doaj +1 more source
Combined heat and power has become an important part of the integrated energy system owing to its advantages in energy conservation and emission reduction.
Zhigang LU +3 more
doaj +1 more source
Orbital elements of barium stars formed through a wind accretion scenario [PDF]
Taking the total angular momentum conservation in place of the tangential momentum conservation, and considering the square and higher power terms of orbital eccentricity e, the changes of orbital elements of binaries are calculated for wind accretion ...
Liang, Y. C. +3 more
core +1 more source

