Results 101 to 110 of about 7,428,319 (298)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Phenomenological Model of Electrotechnical Systems Based on a Synchronous Generator With an Excitation System

Modelling and Simulation in Engineering
We propose a variant of the application of a phenomenological approach using the “black box” concept to the modeling of electrotechnical systems. The method enables obtaining simplified models of a complex electrotechnical system based on a synchronous ...
Volodymyr Moroz, Yaroslav Paranchuk, Volodymyr Konoval, Oleksiy Kuznyetsov   +3 more
doaj   +1 more source

Age of Information-Optimized Differential Protection Strategy for Smart Grids

IEEE Access
Differential protection is a fundamental mechanism in power systems for detecting and isolating faults. However, traditional protection schemes face significant challenges in modern smart grids due to communication delays and the inability to dynamically
Jiajia Fu, Zhongmiao Kang, Ying Zeng, Zanhong Wu   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Adaptive Understanding Framework and Key Technology of Power Grid Fault Disposal Information

Zhongguo dianli
In order to improve the response capacity of power grid fault disposal, an adaptive understanding framework of fault disposal information is proposed. The framework is based on the constructed multi-task collaborative understanding model and the fault ...
Bo TIAN, Yue ZHANG, Fei MENG, Lianfei SHAN, Haiyang GAO, Kun TIAN, Yongtian QIAO   +6 more
doaj   +1 more source

An Application of Joint Spectral Radius in Power Control Problem for Wireless Communications

, 2013
Resource management, including power control, is one of the most essential functionalities of any wireless telecommunication system. Various transmitter power-control methods have been developed to deliver a desired quality of service in wireless ...
Bokharaie, Vahid, Parsaee, Gholamreza
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Graph-Augmented Fault Diagnosis in Power Systems with Imbalanced Text Data: A Knowledge Extraction and Agent-Based Reasoning Framework

Technologies
Fault diagnosis in modern power systems increasingly depends on unstructured operation and maintenance (O&M) logs, yet real-world logs are often small in scale and highly imbalanced across fault types, which degrades the generalizability of standard ...
Yipu Zhang, Yan Guo, Qingbiao Lin, Zhantao Fan, Shengmin Qiu, Xiaogang Wu, Xiaotao Fang   +6 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source