Results 111 to 120 of about 24,854,148 (363)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A real-time control system architecture for industrial power amplifiers

, 2013
Power amplifiers are a highly important component in a range of industrial applications, such as, servo-drives, magnetic resonance imaging, energy systems, and audio.
Lazar, M Mircea, Spinu, V., Spinu, V Veasceslav, Qureshi, F., Lazar, M., Qureshi, FA Faran, Wijnands, CGE Korneel, Wijnands, C.G.E.   +7 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Power Control of a Nonpitchable PMSG-Based Marine Current Turbine at Overrated Current Speed With Flux-Weakening Strategy [PDF]

, 2014
This paper deals with power control strategies for a fixed-pitch direct drive marine current turbine (MCT) when the marine current velocity exceeds the rated value corresponding to the MCT nominal power.
SCUILLER, Franck, CHARPENTIER, Jean-Frederic, Zhou, Zibhin, BENBOUZID, Mohamed, ZHOU, Zhibin, TANG, Tianhao, Charpentier, Jean Fréderic   +6 more
core   +1 more source

Dynamic Reserve Power Point Tracking in Grid-Connected Photovoltaic Power Plants

, 2023
This article introduces a dynamic power reserve control methodology called reserve power point tracking (RPPT) for grid-connected photovoltaic (PV) plants.
Christopher D. Townsend, Glen G. Farivar, Salvador Ceballos, Josep Pou, Farivar, Glen G., Townsend, Christopher D., Beniwal, Neha, Neha Beniwal, Konstantinou, Georgios, Pou, Josep, Narang, Aditi, Hossein Dehghani Tafti, Tafti, Hossein Dehghani, Aditi Narang, Georgios Konstantinou, Ceballos, Salvador   +15 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Power error vector control for doubly-fed induction machine

, 2005
This paper discusses a new control method for variable-speed Doubly-Fed Induction Machine, Power Error Vector Control. The control does not depend on physical parameters of the machine and it has no need to tune parameters, so it is very simple, robust ...
Villate, J. L., Gabiola, I., Martinez De Alegría, I., Andreu, J., Martín, J. L.   +4 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Flexibility-Oriented AC/DC Hybrid Grid Optimization Using Distributionally Robust Chance-Constrained Method

Energies
With the increasing integration of stochastic sources and loads, ensuring the flexibility of AC/DC hybrid distribution networks has become a pressing challenge.
Yue Chen, Qiuyu Lu, Kaiyue Zeng, Yinguo Yang, Pingping Xie   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source