Results 71 to 80 of about 864,788 (299)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

High-Efficiency Multistage Charge Pump Rectifiers Design

Energies
This paper presents an advanced radio frequency (RF)–direct current (DC) power conversion architecture based on a multistage Cockcroft–Walton topology.
Ying Wang, Ce Wang, Shiwei Dong
doaj   +1 more source

Microwave Photonic Frequency Conversion With High Conversion Efficiency and Elimination of Dispersion-Induced Power Fading

IEEE Photonics Journal, 2016
In this paper, a novel microwave photonic mixer based on a single integrated dual-drive dual-parallel Mach–Zehnder modulator (DD-DPMZM) is proposed.
Wu Zhang, Aijun Wen, Yongsheng Gao, Xiaoyan Li, Shuo Shang   +4 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

An all-fibre PM MOPA pumped high-power OPO at 3.82 microns based on large aperture PPMgLN

We report a large aperture PPMgLN based OPO generating 21W of average output power at a slope efficiency of 45%, pumped by the output from a polarization maintaining Ytterbium doped fiber MOPA operating at 1060nm producing 58W of average output power and
Alam, S.-U., Chen, T., Lin, Dejiao, Richardson, D.J., Shen, Y.   +4 more
core   +1 more source

Highly nondegenerate four-wave mixing efficiency of an asymmetric coupled quantum well structure [PDF]

, 1995
An asymmetric coupled quantum well structure is theoretically investigated as a means of tailoring the conversion efficiency of the four-wave mixing process at terahertz detuning rates. In this structure, a coherent electronic oscillation between the two
Paiella, Roberto, Vahala, Kerry J.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

GPVDM simulation of layer thickness effect on power conversion efficiency of CH3NH3PbI3 based planar heterojunction solar cell

International Journal of Energetica, 2018
Perovskite-based solar cell technologies have been a very attractive area of research in recent years. Organic-inorganic perovskite materials are in an increased evolution in power conversion efficiency.
A.bdelkader Hima et al.
doaj  

Electronic amplifier with power supply switching Patent [PDF]

, 1967
Increasing power conversion efficiency of electronic amplifiers by power supply ...
Kramer, M.
core   +1 more source