Results 71 to 80 of about 192,634 (311)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Efficiency of geothermal binary power plants: A Worldwide Review Update [PDF]

, 2015
Estimation of efficiency of a geothermal power plant is a subject of debate with regards to the best method that should be applied. This paper sets the case that different methods are applicable and is dependent on the objective of calculation.
Zarrouk, Sadiq, Odum, Edwin
core  

Effects of environmental factors on the conversion efficiency of solar thermoelectric co-generators comprising parabola trough collectors and thermoelectric modules without evacuated tubular collector [PDF]

, 2014
Solar thermoelectric co-generators (STECGs) are an attractive means of supplying electric power and heat simultaneously and economically. Here we examine the effects of environmental factors on the conversion efficiencies of a new type of STECG ...
Miao, Lei, Shen, Yang, Fisher, C. A. J., Ohno, Kaoru, Lin, Hong, Zhou, Jianhua, Kang, Yi Pu, Li, Chao, Zhang, Ming   +8 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Design of Rectifier with High-Voltage Conversion Gain in 65 nm CMOS Technology for Indoor Light and RF Energy Harvesting

Journal of Sensor and Actuator Networks
In rectifier design, the key parameters are the voltage–conversion ratio and the power conversion efficiency. A new circuit design approach is presented in which a capacitor-based, cross-coupled, differential-driven topology is used to boost the voltage ...
Jefferson Hora, Gene Fe Palencia, Rochelle Sabarillo, Johnny Tugahan, Yichuang Sun, Xi Zhu   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

High efficient series resonant converter using direct power conversion [PDF]

, 2018
This study proposes a high efficient series resonant ac-dc converter. The proposed series resonant converter has a structure integrated with an ac chopper.
Lee, SH, Cho, YW, Cha, WJ, Kim, KT, Kwon, BH   +4 more
core   +1 more source

Microwave Photonic Frequency Conversion With High Conversion Efficiency and Elimination of Dispersion-Induced Power Fading

IEEE Photonics Journal, 2016
In this paper, a novel microwave photonic mixer based on a single integrated dual-drive dual-parallel Mach–Zehnder modulator (DD-DPMZM) is proposed.
Wu Zhang, Aijun Wen, Yongsheng Gao, Xiaoyan Li, Shuo Shang   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source