CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Design of bridgeless Cuk PFC converter based on one-cycle control
For the power factor correction converter circuit structure contains low-frequency rectifier bridge causing the problem of low efficiency, Boost PFC converter can only boost the pressure but can not step down,the proposed bridgeless Cuk PFC converter can
Yu Zhong′an, Ge Tingyu, Liang Jianwei
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Regulated dc-to-dc converter features low power drain [PDF]
A regulated dc-to-dc converter requires negligible standby power for the operation of critical electronic equipment. The main operating circuitry consumes power intermittently according to load conditions, rather than ...
Thornwall, J.
core +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Organic laser power converter for efficient wireless micro power transfer. [PDF]
Wang Y +8 more
europepmc +1 more source
An approach of power loss measurement for converter station and its key equipment
At present, the commonly used power loss calculation method for converter station is mainly based on an analysis and calculation method which needs a large number of system operation and equipment performance parameters, so it is cumbersome and ...
ZHENG Xin +5 more
doaj +1 more source
A novel bidirectional DC-DC converter
For shortages of traditional Buck-Boost converters such as limited output voltage, poor stability, low voltage gain and so on, a novel bidirectional DC-DC converter was designed which used Z-source network to connect DC input power and load.
FANG Xupeng, ZHUANG Jianwei, LI Hui
doaj +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Power Converter Resonant Control for an Unbalanced and Non-Constant Frequency Supply. [PDF]
Rohten J +6 more
europepmc +1 more source

