Results 51 to 60 of about 4,720,670 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis and design of synchronous‐rectified LLC DC–DC converter for LDC of electric vehicles

IET Power Electronics
In electric vehicles (EVs), the low voltage dc‐dc converter (LDC) with synchronous rectifier switches (SRs) can be used to reduce conduction loss caused by the high load current and improve the efficiency.
Xiang Zhou, Shuting Feng, Chaojie Li, Zhengchao Yan   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A non‐isolated single‐switch ultra‐high step‐up DC–DC converter with coupled inductor and low‐voltage stress on switch

IET Power Electronics
This paper presents a non‐isolated single‐switch ultra‐high step‐up (UHSU) DC–DC converter with a three‐winding coupled inductor (CI) which is utilized to achieve ultra‐high voltage gain with a small amount of duty cycle leading to low conduction losses ...
Ali Nadermohammadi, Mohammad Maalandish, Ali Seifi, Pouya Abolhassani, Seyed Hossein Hosseini, Murtaza Farsadi   +5 more
doaj   +1 more source

Experimental analysis of advanced control technique for a five‐phase direct matrix converter based on space vector PWM

IET Power Electronics, 2023
The multiphase matrix converter outperforms the conventional three‐phase system with higher fault tolerance capability and higher power control competency.
Khaliqur Rahman, Adil Sarwar, Mohd Tariq, Shabana Urooj, Farhad Ilahi Bakhsh, Atif Iqbal, Salman Ahmad, Md. Rasidul Islam   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

An asymmetrical quadruple active bridge series resonant DC–DC converter for modular solid‐state transformers

IET Power Electronics
The DC–DC conversion stage of a three‐stage solid‐state transformer is the most challenging due to the combination of high power, medium voltage, and medium frequency. This combination also causes most of the losses in the DC–DC stage.
Saeid Khani, Seyed Hossein Hosseini, Mehran Sabahi   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A reduced‐switch‐count two‐phase interleaved switch‐control‐capacitor LLC converter with accurate current balancing

IET Power Electronics
In this paper, a reduced‐switch‐count two‐phase interleaved LLC converter with precise current balancing is proposed by using switching‐control‐capacitor (SCC) technology.
Xiang Zhou, Xiang Yu, Chaojie Li, Shuting Feng, Hongbo Zhao, Zhengchao Yan   +5 more
doaj   +1 more source

Quasi‐fixed frequency controlled phase modulation LCC resonant converter with a wide power range

IET Circuits, Devices and Systems, 2023
The research on LCC resonant converters has become increasingly popular since the application of the zero‐voltage switching can improve the transmission ability and ensure the high efficiency of the power supplies. In this article, a novel quasi‐definite
Ying Feng, Dejun Kong
doaj   +1 more source