Results 31 to 40 of about 1,975 (307)

A simplified space vector pulse width modulation method for a three‐level four‐leg inverter considering the neutral point potential balance

open access: yesIET Power Electronics, 2023
This paper presents a simple three‐dimensional space vector modulation method in ghγ coordinates for a three‐level four‐leg neutral‐point‐clamped inverter.
Zhi Zhang   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Driver optimization of high power converter based on BIGT reverse conduction loss

open access: yesIET Power Electronics
Bi‐mode Insulated Gate Transistor (BIGT), owing to its notable attributes in power density and compact dimensions, holds promising applications in the realm of high power converters.
Lei Qi   +8 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

An interleaved high step‐up DC–DC converter based on coupled‐inductor

open access: yesIET Power Electronics
This paper proposes an interleaved coupled‐inductor high step‐up direct current (DC)–DC converter. This converter uses a coupled inductor (CI), a voltage multiplier (VM) integrated with a regenerative passive lossless clamp circuit to enhance the voltage
Kamran Karimi   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Hybrid switched‐capacitor‐based boost DC–DC converter with reduced voltage stress

open access: yesThe Journal of Engineering
This article presents the new hybrid switched‐capacitor (SC)‐based transformerless DC–DC converter with a high step‐up capability and common ground features.
Tan Luong Van, Thanh Hai Nguyen
doaj   +1 more source

Phase sequence interchange scheme for suppressing transient cross regulation on the compensator controlled and non‐compensator controlled single‐inductor dual‐output buck converter

open access: yesIET Circuits, Devices and Systems, 2021
Single input multiple output (SIMO) buck converter is a good solution to enhance the area efficiency of the power management unit. Because the SIMO type buck converter uses only one inductor to buffer the transferred energy for the multiple output ports,
Chun‐Hsun Wu   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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