Results 121 to 130 of about 747,618 (290)

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Climate Youth to Power: Coalition Strategy as Social Movement Response to Youth Power Deficits

open access: yesSwiss Journal of Sociology
Based on semi-structured interviews, this article analyzes how activists in the Swiss climate movement deal with their youthfulness. The interviewees associate their youthfulness with institutional, discursive, and economic power deficits that reduce their political assertiveness.
Schaupp, Simon   +2 more
openaire   +1 more source

Energy sector in Gujarat: Performance and prospects [PDF]

open access: yes
With the presence of MNCs and Big corporate players of the country, Gujarat holds a strategic position in the Indian power industry. It has been ranked 2nd in the Power Sector rating Report (2005) of CRISIL-ICRA submitted to the Ministry Of Power, India.
Sudha, venu Menon
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

The Vertical Force-velocity Profile in Male Under-20 National Team Rugby XV Union Players

open access: yesInternational Journal of Strength and Conditioning
Purpose: The main aim of the present study was to describe the Vertical Force-velocity (F-v) profile in male Under-20 (U-20) national team rugby XV union players.
Pablo Pérez-Ifrán   +3 more
doaj   +1 more source

The Effects of Political Fragmentation on Fiscal Deficits in Turkey [PDF]

open access: yes
Recent theoretical and empirical research has considered how differences in political arrangements affecting national policy formation might explain variation in fiscal policies pursued (Volkerink and de Haan, 2001).
Gülcan Önel, Yesim Kustepeli
core  

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Dynamic analysis in the Viner model of mercantilism [PDF]

open access: yes
This paper models the central theme of mercantilism in Jacob Viner's interpretation-power vs plenty-in a framework of modern theory of international finance.
Heng-fu Zou
core  

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

open access: yesAdvanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu   +6 more
wiley   +1 more source

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