Results 101 to 110 of about 13,458,796 (341)
Lensing and Dynamics in Two Simple Steps
, 2012 We present a ready-to-use method to constrain the density distribution in early-type galaxy lenses. Assuming a power-law density profile, then joint use of the virial theorem and the lens equation yields simple formulae for the power-law index (or ...
Agnello, A., Auger, M. W., Evans, N. W.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Case Studies in Thermal EngineeringMulti-dimensional simulations offer a complementary numerical platform to gas turbine experimentation, generating supportive data for training adaptation and artificial intelligence models.
Weimin Deng +5 more
doaj +1 more source
Encircling the dark: constraining dark energy via cosmic density in spheres
, 2016 The recently published analytic probability density function for the mildly non-linear cosmic density field within spherical cells is used to build a simple but accurate maximum likelihood estimate for the redshift evolution of the variance of the ...
Bernardeau, F. +4 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Hybrid Energy Storage Black Start Control Strategy Based on Super Capacitor
EnergiesAddressing the issue of efficient, economical, and reliable operation of a single lead-acid battery (LAB) black start system in complex scenarios, a hybrid energy storage system (HESS) black start scheme based on super capacitors (SCs) is proposed.
Dengfeng Yao +6 more
doaj +1 more source
Design of Direct Injection Jet Ignition High Performance Naturally Aspirated Motorcycle Engines
Designs, 2019 Thanks to the adoption of high pressure, direct injection and jet ignition, plus electrically assisted turbo-compounding, the fuel conversion efficiency of Fédération Internationale de l’Automobile (FIA) F1 engines has been spectacularly ...
Albert Boretti
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Control for nuclear thermionic power source [PDF]
, 1978 A control for a power source which includes nuclear fuel interspersed with thermionic converters, is described. A power regulator maintains a substantially constant output voltage to a variable load, and a control circuit drives a neutron flux regulator ...
Sawyer, C. D.
core +1 more source