Results 111 to 120 of about 7,767,553 (313)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Clinical factors associated with trabecular bone score.

, 2013
Dual-energy X-ray absorptiometry (DXA) measurement of bone mineral density (BMD) is the reference standard for diagnosing osteoporosis but does not directly reflect deterioration in bone microarchitecture.
Hans, D., Leslie, W.D., Manitoba Bone Density, Program, Krieg, M.A.   +3 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Energy Storage Control and Capacity Optimization for Regenerative Braking Power Fluctuation Mitigation Under Port Renewable Energy Integration

IET Renewable Power Generation
To solve the problems of power fluctuations, voltage violations, transformer overloading and restrictions on renewable energy consumption in ports, which are caused by fluctuation of renewables and regenerative braking power, an energy storage system ...
Jingyuan Yin, Junqiang He, Yiyuan Zhang, Zhezhi Chen, Xuelin He   +4 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Dual-Transformer-Based DAB Converter with Asymmetrical Power Transmission and High-Power Density for Electric Vehicles

In this paper, a dual-transformer dual active bridge (DAB) converter with high power density based on the H5 structure is proposed for electric vehicle applications. Additionally, a new dual-frequency switching strategy is presented.
Babalou, Milad, Torkaman, Hossein, Pouresmaeil, Edris, Dezhbord, Morteza   +3 more
core   +1 more source

A high power density single flow zinc-nickel battery with three-dimensional porous negative electrode

, 2013
Low power density (operated current density) is one critical obstacle to the development of single flow zinc nickel batteries (ZNBs). Three-dimensional porous nickel foams (NFs) are first introduced to ZNBs to improve power density.
Zhang, Liqun, Cheng, Yuanhui, Lai, Qinzhi, 赖勤志, Li, Xianfeng, Shi, Dingqin, 张华民, Zhang, Huamin   +7 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimized Breakdown Strength and Crystal Structure for Boosting the Energy Storage Performance of Niobate-Based Glass Ceramics via a B-Site Substitution Strategy

Crystals
Based on the B-site modification strategy, excellent energy storage properties were achieved in this work by substituting Nb with Ta of the same valence in niobate-based glass ceramics.
Kexin Gao, Fei Shang, Yaoyi Qin, Guohua Chen   +3 more
doaj   +1 more source