Results 101 to 110 of about 953,634 (318)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On multiple frequency power density measurements [PDF]
Inverse Problems, 2013 26 pages, 4 ...
openaire +2 more sources
This paper proposes a flattened power electronic design approach to enhance both power density and thermal management performance. As essential components in electrified energy conversion, evaluations of power converters are strongly based on their power
Shuyu Zhang, Zhengwei Dong, Liwei Zhou
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Case Studies in Thermal EngineeringMulti-dimensional simulations offer a complementary numerical platform to gas turbine experimentation, generating supportive data for training adaptation and artificial intelligence models.
Weimin Deng +5 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Hybrid Energy Storage Black Start Control Strategy Based on Super Capacitor
EnergiesAddressing the issue of efficient, economical, and reliable operation of a single lead-acid battery (LAB) black start system in complex scenarios, a hybrid energy storage system (HESS) black start scheme based on super capacitors (SCs) is proposed.
Dengfeng Yao +6 more
doaj +1 more source
Design of Direct Injection Jet Ignition High Performance Naturally Aspirated Motorcycle Engines
Designs, 2019 Thanks to the adoption of high pressure, direct injection and jet ignition, plus electrically assisted turbo-compounding, the fuel conversion efficiency of Fédération Internationale de l’Automobile (FIA) F1 engines has been spectacularly ...
Albert Boretti
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source