Results 51 to 60 of about 3,635,198 (283)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

THE RATIONALE FOR THE USE OF TWO-PHASE SWITCHES FOR THREE-PHASE CONNECTIONS OF DISTRIBUTIVE DEVICE 27.5 KV

open access: yesNauka ta progres transportu, 2008
On the basis of materials of scientists of Moscow and Petersburg State Universities of C Ways and NIIEFAENERGO Ltd.» the author of this article with additions has considered a practical possibility of us bipolar switches on three-phase connections of ...
Yu. Ya. Sheika
doaj  

Individualism and Egalitarianism Can Kill: How Cultural Values Predict Coronavirus Deaths Across the Globe

open access: yesFrontiers in Psychology, 2021
While in some countries, many people have died due to the coronavirus (COVID-19), in other countries, only a few have died. Based on the cultural values theory, our first hypothesis was that in countries that are predominantly individualistic, the number
C. Dominik Güss, Ma. Teresa Tuason
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ROMANIAN STREET LEVEL BUREAUCRACY: A DESCRIPTIVE FOUNDATION

open access: yesTransylvanian Review of Administrative Sciences, 2018
Despite our relatively broad and robust understanding of street level bureaucracy in a Western context, this area of inquiry remains somewhat understudied in an Eastern European context.
Dan Octavian BALICA   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

“Loyalty to organizations” or “loyalty to supervisors”? Research on differential leadership and employee loyalty behavior: A perspective of insiders and outsiders

open access: yesFrontiers in Psychology, 2022
Loyalty has always been a hot topic in the field of organizational behavior, which is of great significance to the operation and management of organizations. Extant studies have found that leadership can have a great impact on loyalty.
Honglie Zhang, Linshen Du, Zhou Jiang
doaj   +1 more source

An average case analysis of the minimum spanning tree heuristic for the range assignment problem [PDF]

open access: yes, 2007
We present an average case analysis of the minimum spanning tree heuristic for the range assignment problem on a graph with power weighted edges. It is well-known that the worst-case approximation ratio of this heuristic is 2.
Boucherie, R.J., Graaf, M. de
core   +2 more sources

Initial Helioseismic Observations by Hinode/SOT [PDF]

open access: yes, 2007
Results from initial helioseismic observations by Solar Optical Telescope onboard Hinode are reported. It has been demonstrated that intensity oscillation data from Broadband Filter Imager can be used for various helioseismic analyses.
Berger, Thomas E.   +14 more
core   +1 more source

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