Results 61 to 70 of about 6,210,481 (210)

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Exploring A Transactional Distance-Based Management Model To Improve Perception Of Efficacy Within Designated Corporate Collaboration Communities [PDF]

open access: yes, 2017
Oil and Gas (O&G) companies are adopting blended learning models to move away from traditional face-to-face training programs that are viewed as costly and less efficient.
Workman, Timothy Peter
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Feminist perspectives on times and spaces in distance learning [PDF]

open access: yes
This study draws on a feminist perspective on time and space, or a feminist time and space literacy, in order to better understand the times and spaces in distance learning.
Raddon, Arwen Evenstar
core  

The preliminary successes and drawbacks of a turn to distance design studio learning.

open access: yes, 2020
It seems the technological campuses of tomorrow have manifested today as an essential and spontaneous response to the COVID-19 world outbreak. This article briefly discusses the current pivot from an on-campus physical design studio curriculum towards a ...
Marshalsey, Lorraine
core  

Flexible Pedagogy, Flexible Practice: Notes from the Trenches of Distance Education [PDF]

open access: yes, 2011
Flexibility has become a watchword in modern education, but its implementation is by no means a straightforward matter. Flexible Pedagogy, Flexible Practice sheds light on the often taken-for-granted assumptions that inform daily practice and examines ...
Elizabeth Burge   +2 more
core  

BPA Prepares for the 21st Century.

open access: yes, 1998
This is a brief review of the state of the Bonneville Power Administration. It reviews BPA`s competitive status, fish and wildlife funding, cost structure of the federal system, subscription sales of electricity, emergency cost recovery, cost reduction ...
United States. Bonneville Power Administration.
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

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