Results 71 to 80 of about 1,548,629 (310)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

FLOATING NEUTRAL DETECTION USING A FORM 2S METER: LARGE DISTRIBUTION LINES WITH MULTIPLE HOUSES AND ROOFTOP PV EFFECT

, 2023
Publisher Copyright: © The Institution of Engineering and Technology 2023.Different concerns about power quality (PQ) arise in electricity distribution systems that use the single-phase three-wire system (120 V/240 V).
Piyasinghe, Lakshan, Arrinda, Amaia, Rodríguez-Seco, Emilio, Vicente, Ibon   +3 more
core   +1 more source

Power Distributing Unit

, 1966
A series of technical drawings in blueprint format illustrating the layout of schematic logic diagrams for a power distribution unit, featuring detailed representations of logic gates and their interconnections.

core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A novel WDOB‐based strategy endows droop‐controlled grid‐forming converters better dynamic and static performance in DC microgrids

IET Power Electronics
The droop control strategy is popularly employed in DC microgrids. However, its virtual resistance will cause voltage deviation and reduce transient response. The DOB‐based method is proven to improve transient response in literature.
Wenqiang Xie, Xian Zheng, Mingming Shi, Tiankui Sun   +3 more
doaj   +1 more source

Centralized Shared Energy Storage Optimization Framework for AC/DC Distribution Systems with Dual-Time-Scale Coordination

Applied Sciences
Conventional shared energy storage (SES) allocation and coordinated operation mechanism are mismatched with the actual time-varying demand of the distribution system, resulting in low utilization of energy storage and renewable energy sources (RES ...
Yidi Zhu, Qian Xiao, Hongjie Jia, Wenbiao Lu, Yu Jin   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

High Impedance Fault Detection on Power Distribution Feeder [PDF]

, 2012
This paper presents an intelligent algorithm using a Takagi Sugeno-Kang (TSK) fuzzy modeling approach based on subtractive clustering to detect high impedance fault. High impedance fault (HIF) is abnormal event on electric power distribution feeder which
Tawafan, Adnan, Sulaiman , Marizan, Ibrahim, Zulkifilie   +2 more
core  

Novel Fault Protection Method for Flexible DC Power Systems

Energies
A fault protection method is proposed for flexible direct-current (DC) power systems based on the cosine similarity of currents in current-limiting reactors.
Genqi Chen, Qing Duan, Caihong Zhao, Haoqing Wang, Guanglin Sha, Jian Gao, Yong Li, Shuiliang Zhou   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source