Results 91 to 100 of about 2,893 (296)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Single-conductor co-planar quasi-symmetry unequal power divider based on spoof surface plasmon polaritons of bow-tie cells

AIP Advances, 2016
In this paper, the spoof surface plasmon polaritons (SSPPs) transmission line (TL) of periodical grooved bow-tie cells is proposed. The complex propagation constant and characteristic impedance of the SSPPs TLs and microstrip lines (MLs) are extracted ...
Yongle Wu, Mingxing Li, Guangyou Yan, Li Deng, Yuanan Liu, Zabih Ghassemlooy   +5 more
doaj   +1 more source

2.45 GHz Band Quadrature Microwave Frequency Discriminators with Integrated Correlators Based on Power Dividers and Rat-Race Hybrids [PDF]

, 2021
A. Rutkowski, Hubert Stadnik
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Invariants in divided power algebras

Journal of Algebra
Let $k$ be an algebraically closed field of characteristic $p>0$, let G=GL_n be the general linear group over $k$, let g=gl_n be its Lie algebra and let $D_s$ be subalgebra of the divided power algebra of g^* spanned by the divided power monomials with exponents $1$.
openaire   +3 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Weakening a theorem on divided powers [PDF]

Transactions of the American Mathematical Society, 1971
We show that if a Hopf algebra has finite dimensional primitives and a primitive lies in arbitrarily long finite sequences of divided powers then it lies in an infinite sequence of divided powers. Introduction. K. Newman has shown us a counter-example to [3, Theorem 2, p. 521]. The theorem states that if H is a cocommutative Hopf algebra over a perfect
openaire   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Fully‐tunable filtering power dividers exploiting dynamic transmission‐zero allocation [PDF]

, 2016
Roberto Gómez‐García, Dimitra Psychogiou, Dimitrios Peroulis   +2 more
openalex   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source