Results 101 to 110 of about 329,512 (244)
Case Studies in Thermal EngineeringThis paper studies the blade cooling under the co-effect of external film extraction and internal impingement cooling with crossflow diverters. The influence of spanwise angle (α) and diameter (Df) of film hole on flow and cooling performance are ...
Juan He +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
ENHANCING TEAMGYM PERFORMANCE WITH POWER TRAINING
Science of Gymnastics JournalPrevious studies have highlighted a strong relationship between mechanical lower limb muscle function and TeamGym performance, specifically in terms of difficulty scores in trampette and tumbling disciplines. To date, no intervention study has explored whether enhancing lower limb muscle function can translate to improved TeamGym performance.
Lindberg, Kolbjørn Andreas +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
This paper proposes a new resilience enhancement strategy for a multi-energy distribution system (MDS) through coordinated reconfiguration of the coupled-power-and-heat network, scheduling of mobile power sources (MPSs) as well as the dispatch of ...
Ghias, Amer M. Y. M. +4 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Gaussianization: Enhancing the Statistical Power of the Power Spectrum
, 2011 2 pages, 2 new figures.
openaire +2 more sources
Power scaling of novel fibre sources
, 2012 This thesis explores novel fibre-based coherent light source architectures and strategies for scaling output power. The research focuses on fibre-based amplified spontaneous emission (ASE) sources with broadband output in the ~1 µm spectral region and on
Cieslak, Rafal
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source