Results 81 to 90 of about 288,130 (267)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Power system operation enhancement modelling using MATLAB/Simulink [PDF]

E3S Web of Conferences
This paper focuses on enhancing power system operations at the injection substation through the integration of renewable energy, modelled and simulated using MATLAB/Simulink.
Somefunn Tobiloba Emmanuel, Ayodeji Olaoye Daniel, Longe Omowunmi Mary   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Muscle-tendon unit design and tuning for power enhancement, power attenuation, and reduction of metabolic cost. [PDF]

J Biomech, 2023
Holt NC, Mayfield DL.
europepmc   +1 more source

On the Power of Context-Enhanced Learning in LLMs

CoRR
We formalize a new concept for LLMs, context-enhanced learning. It involves standard gradient-based learning on text except that the context is enhanced with additional data on which no auto-regressive gradients are computed. This setting is a gradient-based analog of usual in-context learning (ICL) and appears in some recent works.
Xingyu Zhu, Abhishek Panigrahi, Sanjeev Arora   +2 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Multi-Functional Device Based on Superconducting Magnetic Energy Storage

Energies
Presently, there exists a multitude of applications reliant on superconducting magnetic energy storage (SMES), categorized into two groups. The first pertains to power quality enhancement, while the second focuses on improving power system stability ...
Wenyong Guo, Yun Hong, Jianyu Lan, Yahong Yang   +3 more
doaj   +1 more source

Hypothesis Testing for Network Data with Power Enhancement. [PDF]

Stat Sin, 2022
Xia Y, Li L.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Power Enhancement of 265 nm DUV-LED Flip-Chip by HVPE-AlN High-Temperature Annealing. [PDF]

Micromachines (Basel), 2023
Yue W, Liu R, Li P, Zhou X, Liu Y, Yang B, Liu Y, Wang X.   +7 more
europepmc   +1 more source