Results 41 to 50 of about 304,417 (312)
Advances in Mechanical EngineeringNumerical studies on the vane leading edge jet impingement cooling are conducted to analyzed the influence of the cylindrical ribs applied between adjacent jets.
Junfei Zhou +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The quasi-continuous exhaust regime in JET
Nuclear FusionThe quasi-continuous exhaust (QCE) regime is a regime that is naturally type-I ELM-free. It combines the high density at the plasma edge needed for power exhaust with the high normalised energy confinement typical for H-mode operation.
M. Faitsch +19 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Application of automobile emission control technology to light piston aircraft engines [PDF]
, 1976 The possibility was evaluated for achieving the EPA Standards for HC and CO emissions through the use of air-fuel ratio enleanment at selected power modes combined with improved air-fuel mixture preparation, and in some cases improved cooling.
Kittredge, G., Tripp, D.
core +1 more source
Power-dependent speciation of volatile organic compounds in aircraft exhaust [PDF]
, 2012 As part of the third NASA Aircraft Particle Emissions Experiment (APEX-3, November 2005), whole air samples were collected to determine the emission rates of volatile organic compounds (VOCs) from aircraft equipped with three different gas-turbine ...
Anderson, BE +6 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Nuclear FusionIn this work, we cross-compare the state-of-the-art edge plasma codes SOLPS-ITER, SOLEDGE2D, and UEDGE in a reactor-relevant neon-seeded Divertor Tokamak Test scenario at nominal power, extending the simplified test-bed of Moscheni et al (2022 Nucl ...
M. Moscheni +10 more
doaj +1 more source
, 1942 In this study, the heat recovery from exhaust gas at the ACE Power Embilipitiya (Pvt) Ltd (APE) in Sri Lanka was conceptually proposed and evaluated. APE has an installed capacity of 100 MW comprising 14 units of 7.5MW medium speed diesel engines fired ...
Stocking, Collis
core +1 more source