Results 81 to 90 of about 5,034,224 (335)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Methane as an effective hydrogen source for single-layer graphene synthesis on Cu foil by plasma enhanced chemical vapor deposition

, 2013
A single-layer graphene is synthesized on Cu foil in the absence of H2 flow by plasma enhanced chemical vapor deposition (PECVD). In lieu of an explicit H2 flow, hydrogen species are produced during methane decomposition process into their active species
Bae, Berger, Cao, Castro Neto, Delzeit, Denysenko, Dresselhaus, Emtsev, Euijoon Yoon, Eunho Kim, Ferrari, Ferrari, Gao, Geim, Geim, Hash, Heo, Huang, Jae Hong Lee, Jeon, Jongwan Jung, Kim, Kim, Kisu Joo, Li, Li, Li, Meyyappan, Novoselov, Park, Pimenta, Reina, Sahng-Kyoon Jerng, Seung-Hyun Chun, Shen, Sunae Seo, Vlassiouk, Yang, Yong Seung Kim, Young Duck Kim, Yu, Yun Daniel Park, Zhang, Zhou   +43 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamic response of viscous compressible fluids in rigid tubes [PDF]

, 1971
Data on experimental verification of Iberall's analysis applies to such problems as pressure sensing, pneumatic control circuits with bellows, measuring irregular shaped volumes, and transmitting fluid power by pulsating ...
Goldschmied, F. R.
core   +1 more source

Reverse Power Flow Control in a ST-Fed Distribution Grid

IEEE Transactions on Smart Grid, 2018
The massive integration of distributed generation in the grid poses new challenges to the system operators, like the reverse power flow from the low voltage (LV) to medium voltage (MV) grid. In the case of high DG power production and low load absorption,
Giovanni de Carne, G. Buticchi, Zhixiang Zou, Marco Liserre   +3 more
semanticscholar   +1 more source

Real-Time Validation of Power Flow Control Method for Enhanced Operation of Microgrids

Energies, 2020
This paper describes a control methodology for electronic power converters distributed in low-voltage microgrids and its implementation criteria in general microgrid structures.
Hossein Abedini, Tommaso Caldognetto, Paolo Mattavelli, Paolo Tenti   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Concentrated solar CO2 reduction in H2O vapour with >1% energy conversion efficiency

Nature Communications
H2O dissociation plays a crucial role in solar-driven catalytic CO2 methanation, demanding high temperature even for solar-to-chemical conversion efficiencies
Yuqi Ren, Yiwei Fu, Naixu Li, Changjun You, Jie Huang, Kai Huang, Zhenkun Sun, Jiancheng Zhou, Yitao Si, Yuanhao Zhu, Wenshuai Chen, Lunbo Duan, Maochang Liu   +12 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source