Results 71 to 80 of about 660,282 (312)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Security constrained reactive power dispatch in electrical power systems [PDF]

, 1990
With the increased loading and exploitation of the power transmission system and also due to improved optimised operation, the problem of voltage stability and voltage collapse attracts more and more attention .
Chebbo, Ahmad Mustapha
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Local solutions of the optimal power flow problem [PDF]

, 2013
The existence of locally optimal solutions to the AC optimal power flow problem (OPF) has been a question of interest for decades. This paper presents examples of local optima on a variety of test networks including modified versions of common networks ...
Waqquas A. Bukhsh, Grothey, Andreas, Paul A. Trodden, Bukhsh, Waqquas A., Trodden, Paul, Trodden, P., McKinnon, Kenneth, Trodden, Paul A., Bukhsh, Waqquas, Bukhsh, W., Grothey, A., McKinnon, K., Andreas Grothey, Ken I. M. McKinnon, McKinnon, Ken I.M.   +14 more
core   +1 more source

Real-Time Validation of Power Flow Control Method for Enhanced Operation of Microgrids

Energies, 2020
This paper describes a control methodology for electronic power converters distributed in low-voltage microgrids and its implementation criteria in general microgrid structures.
Hossein Abedini, Tommaso Caldognetto, Paolo Mattavelli, Paolo Tenti   +3 more
doaj   +1 more source

Control design and simulation of unified power flow controller [PDF]

IEEE Transactions on Power Delivery, 1998
The unified power flow controller (UPFC) is a solid-state controller which can be used to control active and reactive power flows in a power transmission line. In this paper, the authors propose a control strategy for UPFC in which they control real power flow through the line, while regulating magnitudes of the voltages at its two ports. They design a
Padiyar, KR, Kulkarni, AM
openaire   +3 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Power Flow Control of Interlinked Hybrid Microgrids

, 2012
Microgrids are small reliable grids formed by clustering distributed sources and loads together. They can, in principle, operate at different voltages and frequencies like 50 Hz, 60 Hz, 400 Hz or even dc.
Loh, Poh Chiang, Inam Ullah Nutkani, P.C. Loh, Blaabjerg, Frede, Blaabjerg, Frede; id_orcid, Frede Blaabjerg, Nutkani, Inam Ullah   +6 more
core   +1 more source

Concentrated solar CO2 reduction in H2O vapour with >1% energy conversion efficiency

Nature Communications
H2O dissociation plays a crucial role in solar-driven catalytic CO2 methanation, demanding high temperature even for solar-to-chemical conversion efficiencies
Yuqi Ren, Yiwei Fu, Naixu Li, Changjun You, Jie Huang, Kai Huang, Zhenkun Sun, Jiancheng Zhou, Yitao Si, Yuanhao Zhu, Wenshuai Chen, Lunbo Duan, Maochang Liu   +12 more
doaj   +1 more source