Results 121 to 130 of about 548,931 (316)
Parameter Combination Framework for the Differential Evolution Algorithm
Algorithms, 2019 The differential evolution (DE) algorithm is a popular and efficient evolutionary algorithm that can be used for single objective real-parameter optimization. Its performance is greatly affected by its parameters.
Jinghua Zhang, Ze Dong
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Power and Frequency Control as it Relates to Wind-Powered Generation [PDF]
, 2010 This report is a part of an investigation of the ability of the U.S. power system to accommodate large scale additions of wind generation. The objectives of this report are to describe principles by which large multi-area power systems are controlled and to anticipate how the introduction of large amounts of wind power production might require control ...
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Intelligent Control of Power Generation States
IFAC Proceedings Volumes, 2008 Abstract The topicality of the problem of power generating facility identification is justified against the background of European and Russian power grids interconnection. Intelligent control techniques for power generation states is presented. A technology for estimating the dynamics of power grid's generating facilities participation in overall ...
Natalia N. Bakhtadze +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Grid Connected Inverter Behavior with an Output LC Filter under Voltage Sag Operation [PDF]
, 2009 The aim of this paper is to propose an over current limitation and voltage control strategy for a grid connected inverter with a LC output filter used in distributed generation and in case of voltage sag.
COLAS, Frédéric +2 more
core
Plug-in electric vehicles as demand response to absorb local wind generation in power distribution network [PDF]
, 2013 It has been forecast that by 2020, the penetration of renewable generation in the UK energy mix will reach approximately 15%, predominantly from wind generation, and that the number of electric vehicles (EVs) deployed is also expected to exceed 1 million.
Sikai Huang +9 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source