Results 101 to 110 of about 2,688,256 (303)
Dynamic Characteristics and Experimental Research of Dual-Rotor System with Rub-Impact Fault
Shock and Vibration, 2016 Rub-impact fault model for dual-rotor system was further developed, in which rubbing board is regarded as elastic sheet. Sheet elastic deformation, contact penetration, and elastic damping support during rubbing of sheet and wheel disk were considered ...
Hongzhi Xu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Message Passing for Integrating and Assessing Renewable Generation in a Redundant Power Grid
, 2009 A simplified model of a redundant power grid is used to study integration of fluctuating renewable generation. The grid consists of large number of generator and consumer nodes.
Backhaus, Scott +2 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Parameter Combination Framework for the Differential Evolution Algorithm
Algorithms, 2019 The differential evolution (DE) algorithm is a popular and efficient evolutionary algorithm that can be used for single objective real-parameter optimization. Its performance is greatly affected by its parameters.
Jinghua Zhang, Ze Dong
doaj +1 more source
Effects of Carbon Policies and Technology Change [PDF]
We develop and estimate an index-based measure of expected consumer welfare under various carbon emissions control policies in the electricity generation sector.
Macauley, Molly, Shih, Jhih-Shyang
core
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Scientific ReportsTo enhance the energy efficiency and financial gains of the park integrated energy system (PIES). This paper constructs a bi-level optimization model of PIES-cloud energy storage (CES) based on source-load uncertainty.
Lixin Wang, Jing Cheng, Xu Luo
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source