Results 81 to 90 of about 2,688,256 (303)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Optimized Hierarchical Power Oscillations Control for Distributed Generation Under Unbalanced Conditions

open access: yes, 2017
Control structures have critical influences on converter-interfaced distributed generations (DG) under unbalanced conditions. Most of previous works focus on suppressing active power oscillations and ripples of DC bus voltage.
Chen, Zhe   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optimal Placement of Distributed Energy Storage in Power Networks [PDF]

open access: yes, 2014
We formulate the optimal placement, sizing and control of storage devices in a power network to minimize generation costs with the intent of load shifting.
Bose, Subhonmesh   +2 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Active Dynamic Aggregation Model for Distributed Integrated Energy System as Virtual Power Plant

open access: yesJournal of Modern Power Systems and Clean Energy, 2020
Distributed integrated multi-energy systems (DIMSs) can be regarded as virtual power plants to provide additional flexibility to the power system.
Haotian Zhao   +6 more
doaj   +1 more source

Control system for wind-powered generators [PDF]

open access: yes, 1977
In a system of wind-powered generators, a reliable yet inexpensive control system is desirable. Such a system would be completely automatic so it could be left unattended for long periods. It would respond to electrical representations of data such as bearing temperature, vibration, wind velocity, turbine velocity, torque, or any other pertinent data ...
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Thermodynamic Analysis of a Hybrid Power System Combining Kalina Cycle with Liquid Air Energy Storage

open access: yesEntropy, 2019
Liquid air energy storage (LAES) is a promising energy storage technology in consuming renewable energy and electricity grid management. In the baseline LAES (B-LAES), the compression heat is only utilized in heating the inlet air of turbines, and a ...
Tong Zhang   +4 more
doaj   +1 more source

Heater Control for Thermionic Power Generation [PDF]

open access: yes, 2019
The purpose of this report is to detail the conceptualization, analysis, budget, manufacturing, and assembly the heater for a thermionic energy converter for portable energy generation.
Kearney, Patrick   +2 more
core   +1 more source

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