Results 51 to 60 of about 468,485 (314)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Flexible unbalanced control with peak current limitation for virtual synchronous generator under voltage sags

Journal of Modern Power Systems and Clean Energy, 2017
Virtual synchronous generator (VSG) is grid-friendly for integrating distributed generations (DGs) since it can emulate the operation mechanism of traditional synchronous generator (SG).
Tianwen ZHENG, Laijun CHEN, Yan GUO, Shengwei MEI   +3 more
doaj   +1 more source

An Improved Beetle Swarm Algorithm Based on Social Learning for a Game Model of Multiobjective Distribution Network Reconfiguration

IEEE Access, 2020
With the increased distributed generation (DG) and electric vehicle (EV) load penetration in distribution networks, it is more difficult to ensure the safe and economic operation of the distribution networks because of the great volatility and randomness
Qian Chen, Weiqing Wang, Haiyun Wang, Jiahui Wu, Jie Wang   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Promoting Effect of Inorganic Alkali on Carbon Dioxide Adsorption in Amine-Modified MCM-41

Energies, 2016
Three kinds of inorganic alkali are introduced into tetraethylenepentamine (TEPA) and polyethyleneimine (PEI)-modified MCM-41 as the CO2 adsorbents. X-ray diffraction, N2 adsorption, fourier-transform infrared and thermo gravimetric analysis are used to ...
Yang Teng, Lijiao Li, Gang Xu, Kai Zhang, Kaixi Li   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A General Intelligent Optimization Algorithm Combination Framework with Application in Economic Load Dispatch Problems

Energies, 2019
Recently, a population-based intelligent optimization algorithm research has been combined with multiple algorithms or algorithm components in order to improve the performance and robustness of an optimization algorithm.
Jinghua Zhang, Ze Dong
doaj   +1 more source

Electricity allocation strategy for on‐site hydrogen refueling stations in the forward and spot markets

IET Renewable Power Generation, 2022
Green hydrogen in fuel cell vehicles (FCVs) is a promising alternative in the transportation sector. However, high hydrogen costs hinder progress. An on‐site hydrogen refueling station (OHRS) can avoid hydrogen transportation and participate in the ...
Sirui Wu, Jin Lin, Jiarong Li, Yonghua Song   +3 more
doaj   +1 more source