Results 91 to 100 of about 272,972 (308)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A Study on the Nourishing Number of Graphs and Graph Powers [PDF]

open access: yesMathematics, 2015
Let \(\mathbb{N}_{0}\) be the set of all non-negative integers and \(\mathcal{P}(\mathbb{N}_{0})\) be its power set. Then, an integer additive set-indexer (IASI) of a given graph \(G\) is defined as an injective function \(f:V(G)\to \mathcal{P}(\mathbb{N}_{0})\) such that the induced edge-function \(f^+:E(G) \to\mathcal{P}(\mathbb{N}_{0})\) defined by \
Naduvath, Sudev, Augustine, Germina
openaire   +5 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The Power Graph of a Dihedral Group

open access: yes, 2022
Graph theory is one of the topics in mathematics that is quite interesting to study because it is applicable and can be combined with other mathematical topics such as group theory.
Wardhana, I Gede Adhitya Wisnu   +3 more
core   +2 more sources

On the Extended Adjacency Eigenvalues of Graphs and Applications

open access: yesMathematics
Let Aex(G) be the extended adjacency matrix of G. The eigenvalues of Aex(G) are called extended adjacency eigenvalues of G. The sum of the absolute values of eigenvalues of the Aex-matrix is called the extended adjacency energy Eex(G) of G. In this paper,
Hilal A. Ganie, Amal Alsaluli
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Smarandache Directionally n-Signed Graphs — A Survey [PDF]

open access: yes, 2013
For graph theory terminology and notation in this paper we follow the book [3]. All graphs considered here are finite and simple.
P. Siva Kota Reddy, Reddy, P.Siva Kota
core   +1 more source

Signless Laplacian spectrum of power graphs of finite cyclic groups

open access: yesAKCE International Journal of Graphs and Combinatorics, 2020
In this paper, we have studied the Signless Laplacian spectrum of the power graph of finite cyclic groups. We have shown that is an eigen value of Signless Laplacian of the power graph of with multiplicity at least In particular, using the theory of ...
Subarsha Banerjee, Avishek Adhikari
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

On groups with specified quotient power graphs [PDF]

open access: yesInternational Journal of Group Theory, 2016
. In this paper we study some relations between the power andquotient power graph of a finite group. These interesting relations motivateus to find some graph theoretical properties of the quotient power graphand the proper quotient power graph of a ...
Mostafa Shaker, Mohammadali Iranmanesh
doaj  

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