Results 41 to 50 of about 180,098 (263)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
ON SPECIFIC LOSSES OF TRANSFORMER POWER
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014 Zone searching for optimum transformer loading according to minimum of total active power losses has been carried out in the paper.
A. A. Gonchar
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
OPTIMAL LOSSES IN POWER DISTRIBUTION NETWORKS
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014 The distributed power network 0,38–10 kV is investigated and the conditions for providing optimal load of network and technically reasonable (minimal) values of electricity consumption are determined.
M. I. Fursanov
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Electrical model for power losses in direct power injection
IET Science, Measurement & Technology, 2007 This paper introduces a study of power losses in a populated board under direct power injection (DPI), used to measure the immunity of integrated circuits to conducted continuous-wave interference. The relative contributions of all loss sources are evaluated, leading to the preeminence of conductive and dielectric losses over radiated ones, and an ...
Alaeldine, Ali +3 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Power Losses Estimation for Visualization of Heat Distribution
Advances in Electrical and Electronic Engineering, 2020 For designing power electronics, especially high-power-density systems, power loss estimation is a very important step in the design process. The estimation of losses without using a mathematical method, but instead using a simulation approach can ...
Patrik Resutik, Slavomir Kascak
doaj +1 more source