Results 61 to 70 of about 170,154 (262)
Optimizing Power Losses and Efficiency of Broadband Parallel-Circuit Class-E Power Amplifier
This paper presents a design method for a watt-level high-efficiency broadband power amplifier (BPA) with a generalized parallel-circuit (PC) Class-E model.
Heng Lu, Jianliang Jiang, Hengli Zhang
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Model of Electric and Heat Balance of Biogas Station
This paper deals with the model of a biogas station. The introduction provides a description of principle employed in this model. The model works with data reflecting the quantity and type of the input biomass to determine the potential energy and offer ...
Jiri Jansa, Zdenek Hradilek
doaj +1 more source
Power Losses Estimation for Visualization of Heat Distribution
For designing power electronics, especially high-power-density systems, power loss estimation is a very important step in the design process. The estimation of losses without using a mathematical method, but instead using a simulation approach can ...
Patrik Resutik, Slavomir Kascak
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Refined calculation of energy modes of a frequency-regulated induction motor
Purpose. To obtain analytical dependencies for the precise calculation of the stator current of a frequency-regulated three-phase short-circuited induction motor and to estimate the components of its main electrical power losses, which are spent on the ...
V. A. Volkov, N. L. Antonov
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Design of Hybrid Power Systems with Energy Losses
Pinch Analysis has been recently extended into the design of hybrid power systems to determine the maximum power recovery and battery storage capacity.
N.E. Mohammad Rozali +3 more
doaj +1 more source
Power loss mechanisms in pathological tracheas
The effort required to inhale a breath of air is a critically important measure in assessing airway function. Although the contribution of the trachea to the total flow resistance of the airways is generally modest, pathological alterations in tracheal geometry can have a significant negative effect.
Bates, A.J. +5 more
openaire +3 more sources

