Results 71 to 80 of about 1,542,691 (303)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Analysis of rolling bearing power loss models for twin screw oil injected compressor [PDF]

open access: yes, 2019
The mechanical losses inside a screw compressor limit the performance of the compressor in terms of efficiency. These losses arise due to relative motion between elements inside the screw compressor.
  +10 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Refined calculation of energy modes of a frequency-regulated induction motor

open access: yesElectrical engineering & Electromechanics
Purpose. To obtain analytical dependencies for the precise calculation of the stator current of a frequency-regulated three-phase short-circuited induction motor and to estimate the components of its main electrical power losses, which are spent on the ...
V. A. Volkov, N. L. Antonov
doaj   +1 more source

Finite-sample Analysis of M-estimators using Self-concordance [PDF]

open access: yes, 2018
We demonstrate how self-concordance of the loss can be exploited to obtain asymptotically optimal rates for M-estimators in finite-sample regimes. We consider two classes of losses: (i) canonically self-concordant losses in the sense of Nesterov and ...
Bach, Francis, Ostrovskii, Dmitrii
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Power Losses Estimation for Visualization of Heat Distribution

open access: yesAdvances in Electrical and Electronic Engineering, 2020
For designing power electronics, especially high-power-density systems, power loss estimation is a very important step in the design process. The estimation of losses without using a mathematical method, but instead using a simulation approach can ...
Patrik Resutik, Slavomir Kascak
doaj   +1 more source

Renewable power for lean desktops in media applications [PDF]

open access: yes, 2009
An integration of solar microgeneration to supply a low-power IT desktop, using the Power over Ethernet standards IEEE 802.3af/at as a low power distribution network avoiding transformer losses from DC generation to mains power AC and back to low-voltage
Counsell, John M.   +2 more
core  

Electrical model for power losses in direct power injection

open access: yesIET Science, Measurement & Technology, 2007
This paper introduces a study of power losses in a populated board under direct power injection (DPI), used to measure the immunity of integrated circuits to conducted continuous-wave interference. The relative contributions of all loss sources are evaluated, leading to the preeminence of conductive and dielectric losses over radiated ones, and an ...
Alaeldine, Ali   +3 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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