Results 71 to 80 of about 12,187,390 (343)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Designing power inductors: practical solutions [PDF]

open access: yes, 2011
An overview of losses and thermal aspects if power inductors is given. Most of the time core losses are given only for sine square wave, but users use it in square waves. Also bulk currents affect losses in larger inductors.
Van den Bossche, Alex
core   +1 more source

THz emission from a stacked coherent flux-flow oscillator: non-local radiative boundary conditions and the role of geometrical resonances

open access: yes, 2010
I derive simple non-local dynamic boundary conditions, suitable for modelling of radiation emission from stacked Josephson junctions, and employ them for analysis of flux-flow emission from intrinsic Josephson junctions in high-$T_c$ superconductors.
Krasnov, V. M.
core   +1 more source

Optimizing wind farm cable routing considering power losses

open access: yesEuropean Journal of Operational Research, 2017
Wind energy is the fastest growing source of renewable energy, but as wind farms are getting larger and more remotely located, installation and infrastructure costs are rising.
Martina Fischetti, David Pisinger
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

OPTIMAL LOSSES IN POWER DISTRIBUTION NETWORKS

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014
The distributed power network 0,38–10 kV is investigated and the conditions for providing optimal load of network and technically reasonable (minimal) values of electricity consumption are determined.
M. I. Fursanov
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Multipulse current source offers low power losses and high reliability [PDF]

open access: yes, 1967
Pulse current source uses low loss, high reliability, LC circuits to provide the necessary high impedance for magnetic memory cores, frequently used in digital computational equipment.

core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Finite-sample Analysis of M-estimators using Self-concordance [PDF]

open access: yes, 2018
We demonstrate how self-concordance of the loss can be exploited to obtain asymptotically optimal rates for M-estimators in finite-sample regimes. We consider two classes of losses: (i) canonically self-concordant losses in the sense of Nesterov and ...
Bach, Francis, Ostrovskii, Dmitrii
core   +2 more sources

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