Results 51 to 60 of about 1,588,214 (308)
A Best Possible Double Inequality for Power Mean
Journal of Applied Mathematics, 2012 We answer the question: for any p,q∈ℝ with p≠q and p≠-q, what are the greatest value λ=λ(p,q) and the least value μ=μ(p,q), such that the double inequality Mλ(a,b)
Yong-Min Li, Bo-Yong Long, Yu-Ming Chu
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A certain new Gauss sum and its fourth power mean
AIMS Mathematics, 2020 The main purpose of this paper is using the elementary methods and the properties of the Legendre symbol to study the computational problem of the fourth power mean of a certain generalized quadratic Gauss sum, and give two exact calculating formulae for
Yan Zhao, Wenpeng Zhang, Xingxing Lv
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
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The Mean of Power by Philosophy of Hannah Arendt
Revista Brasileira de Filosofia do Direito, 2016 The issue analyzes the existent relation between power and violence by philosophy of Hannah Arendt. The tradition of politic thought tends to concern power from the approuch of command and obedience, in other words, the capacity of influence and control ...
Rene Erick Sampar
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