Results 71 to 80 of about 6,587,950 (298)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An Optimal Double Inequality between Power-Type Heron and Seiffert Means

open access: yesJournal of Inequalities and Applications, 2010
For , the power-type Heron mean and the Seiffert mean of two positive real numbers and are defined by , ; , and , ; , , respectively.
Wang Miao-Kun, Qiu Ye-Fang, Chu Yu-Ming
doaj   +2 more sources

Approaching the Power Logarithmic and Difference Means by Iterative Algorithms Involving the Power Binomial Mean

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2011
Introducing the notion of cross means we give iterative algorithms involving the power binomial mean and converging to the power logarithmic and difference means. At the end, we address a list of open problems derived from our present work.
Mustapha Raïssouli
doaj   +1 more source

Wind and Photovoltaic Generation Scene Division Based on Improved K-means Clustering

open access: yes发电技术, 2020
In view of the uncertainty of power generation in renewable energy, especially wind power and photovoltaic power generation, the improved K-means clustering method was used to segment the state of power generation.
Xuewei SONG, Yuyao LIU
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Optimization of the Contracted Electric Power by Means of Genetic Algorithms

open access: yesEnergies, 2019
An adequate selection of an energy provider and tariff requires us to analyze the different alternatives to choose one that satisfies your needs. In particular, choosing the right electricity tariff is essential for reducing company costs and improving ...
Alfredo Alcayde   +3 more
doaj   +1 more source

The soft notion of China's 'soft power' [PDF]

open access: yes, 2011
· Although debates over Chinese soft power have increased in recent years, there is no shared definition of what ‘soft power’ actually means. The definition seems to change depending on what the observer wants to argue.
Breslin, Shaun
core  

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