Results 81 to 90 of about 6,587,950 (298)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Basic hemp protection means for a power substation: a quick guide

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2017
Protection of modern sensitive electronics used in power systems (Digital Protective Relays - DPR, control devices and microprocessor-based communication equipment, etc.) against High Altitude Electromagnetic Pulse (HEMP), and also protection of power ...
V. I,. Gurevich
doaj   +1 more source

God\u27s Activity in Today\u27s World: a Review Essay on Kingdom Triangle [PDF]

open access: yes, 2009
In this review essay, I consider J. P. Moreland\u27s Kingdom Triangle as a recent example that takes seriously the incursion of God\u27s Kingdom into the human realm.
Habermas, Gary R.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

REGULATION OF REACTIVE POWER PRODUCED BY DOUBLY FED INDUCTION WIND GENERATORS [PDF]

open access: yes, 2018
Study the methods of providing balance of reactive power by means of the voltage applied to the rotor of doubly fed induction wind ...
IVANOV, Oleksii, LIABAHOVA, Tetiana
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The optimization for the inequalities of power means

open access: yesJournal of Inequalities and Applications, 2006
Let be the th power mean of a sequence of positive real numbers, where , and . In this paper, we will state the important background and meaning of the inequality ; a necessary and sufficient condition and another interesting sufficient condition that
Wen Jiajin, Wang Wan-Lan
doaj  

Duty cycle testing and performance evaluation of the SM-229 teleoperator [PDF]

open access: yes, 1985
The first known experimental studies and analyses of teleoperator performance for specific duty cycles are discussed. The results are presented in two distinct areas as position usage patterns, and as three-dimensional power grids.
Kuban, Daniel P., Stoughton, Robert S.
core   +1 more source

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