Results 51 to 60 of about 752,862 (305)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evaluation of mismatch power loss in a PV string composed of series-connected modules: Theory versus experiment

Ain Shams Engineering Journal
Ground-installed PV power-systems are usually built in parallel-rows; each is composed of series-connected modules. With time, some modules got-polluted or −shaded differently. On damage, some modules may be replaced by others of different ratings.
Reham Kamal, Mazen Abdel-Salam, Mohamed Nayel   +2 more
doaj   +1 more source

Junction Temperature Control System to Increase the Lifetime of IGBT-Power-Modules in Synchronous Motor Drives Without Affecting Torque and Speed

IEEE Open Journal of Power Electronics, 2020
Load changes of electrical machines driven by inverters cause temperature swings of the semiconductor devices in IGBT modules of the inverters. These temperature swings lead to mechanical strain in the different material layers of the IGBT-power-modules ...
Julian Wolfle, Maximilian Nitzsche, Johannes Ruthardt, Jorg Roth-Stielow   +3 more
doaj   +1 more source

Low power wireless sensor network for structural health monitoring of buildings using MEMS strain sensors and accelerometers [PDF]

, 2012
Within the MEMSCON project, a wireless sensor network was developed for structural health monitoring of buildings to assess earthquake damage. The sensor modules use custom-developed capacitive MEMS strain and 3D acceleration sensors and a low power ...
Bertsch, Nicolas, Brebels, Steven, Saillen, Nicolas, Santana-Corte, Juan, Sterken, Tom, Torfs, Tom, Trapani, Davide, Van den Hoven, Richard, Zonta, Daniele   +8 more
core  

Clock and Trigger Synchronization between Several Chassis of Digital Data Acquisition Modules

, 2007
In applications with segmented high purity Ge detectors or other detector arrays with tens or hundreds of channels, where the high development cost and limited flexibility of application specific integrated circuits outweigh their benefits of low power ...
Fallu-Labruyere, A., Grudberg, P., Hennig, W., Miller, D., Starosta, K., Tan, H., Vaman, C., Walby, M., Warburton, W. K.   +8 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Assessing the Impact of Water Cooling on PV Modules Efficiency

Energies, 2020
The article presents the results of research on the efficiency of photovoltaic (PV) modules cooled with water. The aim of the experiment was to improve the working conditions of solar modules.
Wojciech Luboń, Grzegorz Pełka, Mirosław Janowski, Leszek Pająk, Michał Stefaniuk, Jarosław Kotyza, Paweł Reczek   +6 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source