Results 71 to 80 of about 6,339,547 (295)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Selecting Operating Conditions of Power MOSFETs in a Power Cycling Test Based on Thermal Time Constants

Energies
This paper presents the results of research on the effect of temperature on damage processes occurring in power MOSFETs. The impact of changes in the activation energy of selected mechanisms initiating the damage process in power MOSFETs during ...
Krzysztof Górecki, Paweł Górecki
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Use of a multi-objective teaching-learning algorithm for reduction of power losses in a power test system

Dyna, 2014
Este artículo presenta un algoritmo de enseñanza-aprendizaje multi-objetivo basado en descomposición para resolver el problema del despacho óptimo de potencia reactiva (ORPD).
Miguel A. Medina, Juan M. Ramirez, Carlos A. Coello, Swagatam Das   +3 more
doaj  

Non-central t distribution and the power of the t test: A rejoinder [PDF]

Tutorials in Quantitative Methods for Psychology, 2011
Non-central t distribution needed for assessing the power of the t test is described. Three approximations are compared and their merits discussed in regard to simplicity and accuracy.
Denis Cousineau, Louis Laurencelle
doaj  

The Design and Life Test of a Multifunction Power Amplifier for Space Application

Active and Passive Electronic Components, 2016
A new multifunction power amplifier (MFPA) is designed and fabricated for the application of point-to-point K-Band backhaul TR module. A DC temperature life test was performed to model the up-limit temperature effect of the designed MFPA under space ...
Xiuqin Xu, Hui Xu, Yongheng Shang, Zhiyu Wang, Yang Wang, Liping Wang, Hao Luo, Zhengliang Huang, Faxin Yu   +8 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Statistical power of a test – an analysis of a test’s power, its role in the research methodology and the interpretation of (non-)significance in a low- (high-) powered test

Przegląd Psychologiczny, 2021
abstract
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source