Results 71 to 80 of about 189,528,022 (311)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Tractor Testing; PTO Test; Jeep
, 1949 "Willys Jeep being tested at Nebraska Tractor Test Laboratory." Willys-Overland Motors Jeep CJ-3A Universal is shown inside the tractor test lab. After WWII, with many jeeps being surplus and a lack of tractors, the Jeep as well as the Dodge Power wagon ...
Nebraska Tractor Test Laboratory
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Revista Colombiana de Estadística, 2010 Se propone una prueba para la hipótesis de similitud de dos secuencias dicotómicas ordenadas. Un estudio de potencia basado en simulación indica que la prueba propuesta mantiene su tamaño bajo la hipótesis nula y que su potencia crece adecuadamente con ...
RAMÓN GIRALDO HENAO +1 more
doaj
Reliability, Validity and Minimal Detectable Change of a Power Leg Press Test in Individuals with Cerebral Palsy. [PDF]
Phys Occup Ther Pediatr, 2023 Pontiff M, Li L, Moreau NG.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Tractor Testing; Belt Power; Oliver
, 1949 Oliver HG during belt power test.
Nebraska Tractor Test Laboratory
core
A combined tree growing technique for block-test scheduling under power constraints [PDF]
, 2001 A tree growing technique is used here together with classical scheduling algorithms in order to improve the test concurrency having assigned power dissipation limits.
Wang, Xiaojun +6 more
core +2 more sources
Novel score test to increase power in association test by integrating external controls. [PDF]
Genet Epidemiol, 2021 Li Y, Lee S.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source