Results 51 to 60 of about 8,289,953 (304)

High-Efficiency Asymmetric Forward-Flyback Converter for Wide Output Power Range

open access: yes, 2018
This paper proposes an asymmetric forward-flyback dc-dc converter that has high power-conversion efficiency e over a wide output power range. To solve the problem of ringing in the voltage of the rectifier diodes and the problem of duty loss in the ...
Choe, Hyung-Jin   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Work rate adjustments needed to maintain heart rate and RPE during high-intensity interval training in the heat

open access: yesFrontiers in Physiology
IntroductionHigher work rates may be sustainable when maintaining target rating of perceived exertion (RPE) compared to maintaining target heart rate (THR) during high-intensity interval training (HIIT) exercise in hot conditions, but may also result in ...
Hillary A. Yoder   +5 more
doaj   +1 more source

Technical Determinants of On-Water Rowing Performance

open access: yesFrontiers in Sports and Active Living, 2020
Purpose: Research establishing relationships between measures of rowing technique and velocity is limited. In this study, measures of technique and their effect on rowing velocity were investigated.Methods: Ten male singles, eight female singles, three ...
Ana C. Holt   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Single-Inductor Multiple-Output (SIMO) Buck Hybrid Converter for Simultaneous Wireless and Wired Power Transfer

open access: yes, 2020
In this paper, a non-isolated single-inductor multiple-output (SIMO) DC-AC buck-derived hybrid converter for simultaneously driving multiple independent AC and DC loads by employing only a single inductor in the power stage, is proposed.
Tan, SC, Hui, SY, Lee, ATL, JIN, W
core   +1 more source

Bilateral index, power, force, and velocity during bench press with different loads in male handball players

open access: yesFrontiers in Physiology, 2023
Bilateral index for upper limbs was determined for maximal force, speed and power in 18 male handball players. Variables were individually assessed with a functional electromechanical dynamometer during unilateral and bilateral bench press push-off for ...
Andrés González-Ramírez   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Performance improvement of PV panel using water cooling technology under Egyptian conditions [PDF]

open access: yesJournal of Engineering Research - Egypt, 2019
This paper presented the effect of water cooling technique on the performance of PV panels under Egyptian condition. In this study three different positions of the cooling technique was studied (front side, backside and both sides simultaneously).
A. Khalil   +2 more
doaj   +1 more source

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