Results 61 to 70 of about 8,289,953 (304)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Output-power test-results graph.
(a) Power-output test chart (b) Output-power flatness in frequency band (c) P1dB output power at 13.75GHz and 14GHz frequency points (d) P1dB output power at 14.25GHz and 14.5GHz frequency points.
Jinsong Liu (6516) +8 more
core +1 more source
Journal of the International Society of Sports NutritionBackground Caffeine, widely recognized as an ergogenic aid, has undergone extensive research, demonstrating its effectiveness to enhance endurance performance.
Bin Chen +5 more
doaj +1 more source
Repeated Menthol Mouth Swilling Affects Neither Strength nor Power Performance
Sports, 2020 This study aimed to assess the effects of repeated menthol mouth swilling upon strength and power performance. Nineteen (10 male) participants completed familiarisation and experimental trials of repeated menthol mouth swilling (0.1% concentration) or ...
Russ Best +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Management of the Output Electrical Power in Thermoelectric Generators
, 2019 Thermoelectric Generators (TEGs) are devices for direct conversion of heat into electrical power and bear a great potential for applications in energy scavenging and green energy harvesting.
Francesco Rossella +2 more
core +1 more source
Entropy, 2020 A theoretical model of an open combined cycle is researched in this paper. In this combined cycle, an inverse Brayton cycle is introduced into regenerative Brayton cycle by resorting to finite-time thermodynamics.
Lingen Chen, Huijun Feng, Yanlin Ge
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Piezoelectric Energy Harvesting: Enhancing Power Output by Device Optimisation and Circuit Techniques [PDF]
, 2010 Energy harvesting; that is, harvesting small amounts of energy from environmental sources such as solar, air flow or vibrations using small-scale (≈1cm 3 ) devices, offers the prospect of powering portable electronic devices such as GPS receivers and
Worthington, Emma
core +3 more sources