Results 81 to 90 of about 8,289,953 (304)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Effects of Unloaded vs. Loaded Plyometrics on Speed and Power Performance of Elite Young Soccer Players

Frontiers in Physiology, 2017
The purpose of this study was to investigate the effects of loaded and unloaded plyometric training strategies on speed and power performance of elite young soccer players. Twenty-three under-17 male soccer players (age: 15.9 ± 1.2 years, height: 178.3 ±
Ronaldo Kobal, Lucas A. Pereira, Vinicius Zanetti, Rodrigo Ramirez-Campillo, Irineu Loturco   +4 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Compact high-power tunable three-level operation of double cladding Nd-doped fiber laser [PDF]

, 2005
We present a compact high-power continuous-wave tunable neodymium-doped double cladding fiber laser operating on three-level 4F3/2 - 4I9/2 transition with a maximum output power up to 810 mW.
Nilsson, J., Fu, L.B., Ibsen, M., Richardson, D.J., Grudinin, A.B., Payne, D.N.   +5 more
core   +1 more source

The Impact of Isoinertial Training on Thigh Muscle Volume: Ultrasound and Dynamometric Evaluation

Bioengineering
Muscle imbalance due to reduced muscular endurance is a significant risk factor. Thus, for the lower limb, muscle imbalance is one of the most common causes of traumatic injury.
Ligia Rusu, Aurora Dobre Ungureanu, Alexandru Chivaran, Mihnea Ion Marin, Mihai Robert Rusu, Andrei Spinu, Mara Marin, Gabriel Buciu, Mirela Lucia Calina   +8 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

A Single-Stage Two-Switch PFC Rectifier With Wide Output Voltage Range and Automatic AC Ripple Power Decoupling [PDF]

, 2016
Conventional single-phase power-factor-correction (PFC) rectifiers with active power decoupling capability typically require more than three active switches in their circuits.
Tan, SC, Hui, SYR, QI, W, Li, S, Ron Hui, SY   +4 more
core   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Prediction of on-water performance in outrigger canoeing using laboratory tests: the influence of sex and anthropometric characteristics

Frontiers in Sports and Active Living
The relationship between laboratory-based ergometer performance, body size, and on-water outrigger canoe (OC) racing remains unclear. This study examined associations between anthropometric characteristics, ergometer-derived performance, and on-water ...
Filipe Estácio Costa, Rafael Lima Kons, Fabrizio Caputo, Juliano Dal Pupo   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source