Results 41 to 50 of about 183,087 (265)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Diverging nonlocal fields: Operationalizing critical disability physics identity with neurodivergent physicists outside academia

Physical Review Physics Education Research
Science, technology, engineering, and mathematics (STEM) education research and physics education research, in particular, are currently struggling with a dearth of research into understanding the experiences and identity development of neurodivergent ...
Liam G. McDermott, Nazeer A. Mosley, Geraldine L. Cochran   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Human Brain Dynamics Reflect the Correctness and Presentation Modality of Physics Concept Memory Retrieval

Frontiers in Human Neuroscience, 2020
Human memory retrieval is the core cognitive process of the human brain whenever it is processing the information. Less study has focused on exploring the neural correlates of the memory retrieval of scientific concepts when presented in word and picture
Chih-Ping Liang, Hsiao-Ching She, Li-Yu Huang, Wen-Chi Chou, Sheng-Chang Chen, Tzyy-Ping Jung   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The ground states of hidden-charm tetraquarks and their radial excitations

European Physical Journal C: Particles and Fields
Inspired by the great progress in the observations of charmonium-like states in recent years, we perform a systematic analysis about the ground states and the first radially excited states of $$qc\bar{q}\bar{c}$$ q c q ¯ c ¯ (q = u/d and s) tetraquark ...
Guo-Liang Yu, Zhen-Yu Li, Zhi-Gang Wang, Bin Wu, Ze Zhou, Jie Lu   +5 more
doaj   +1 more source

Microscopic nature of the photon strength function: stable and unstable Ni and Sn isotopes

EPJ Web of Conferences, 2015
The pygmy-dipole resonances and photon strength functions in stable and unstable Ni and Sn isotopes are calculated within the microscopic self-consistent version of the Extended Theory of Finite Fermi Systems that includes the QRPA and phonon coupling ...
Achakovskiy Oleg, Avdeenkov Alexander, Goriely Stephane, Kamerdzhiev Sergei, Krewald Siegfried, Voitenkov Dmitriy   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Breakdown Characteristics of Propylene Carbonate and Deionized Water Under Nanosecond Pulsed Voltages

Energies
Propylene carbonate (PC) has several advantages, including a high dielectric constant, high resistivity, and excellent environmental adaptability, making it a promising candidate as a novel energy storage medium for pulse forming lines (PFL).
Qingheng Lu, Lin Chen, Feng Li, Jihao Jiang, Jie Wang, Yue Zhao, Wenhui Han, Bing Wei, Ziping Huang   +8 more
doaj   +1 more source

Physics in geothermal power plants

Journal of Physics: Conference Series, 2019
Abstract Many students dont like physics because they feel far away from physics. Therefore physics must be made closer to students through contextual physics. This paper wants to describe the physical concepts that exist in geothermal power plants. The method used is Research and Development (R & D) with the ADDIE model design.
D Nasrudin, D Nopilawati, C Rochman, Y N Rahayu, M F Millah, D Mulhayatiah   +5 more
openaire   +1 more source