Results 41 to 50 of about 5,016,292 (324)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Two Points Taylor’s Type Representations for Analytic Complex Functions with Integral Remainders
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2021 In this paper we establish some two point weighted Taylor’s expansions for analytic functions f : D ⊆ ℂ→ ℂ defined on a convex domain D. Some error bounds for these expansions are also provided.
Dragomir Silvestru Sever
doaj +1 more source
Frontiers in Physics, 2023 A novel analytical solution to the neutron diffusion equation is proposed in this study using the residual power series approach for both spherical and hemispherical fissile material reactors.
Ahmad El-Ajou +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
An irreducibility criterion for power series
, 2016 We prove an irreducibility criterion for polynomials with power series coefficients generalizing previous known results concerning quasi-ordinary ...
Rond, Guillaume, Schober, Bernd
core +3 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Известия Иркутского государственного университета: Серия "Математика", 2020 The paper deals with the problem of the motion of a heat wave with a specified front for a general nonlinear parabolic heat equation. An unknown function depends on two variables. Along the heat wave front, the coefficient of thermal conductivity and the
A.L. Kazakov, L.F. Spevak
doaj +1 more source
Diffusion-Wave Type Solutions to the Second-Order Evolutionary Equation with Power Nonlinearities
Mathematics, 2022 The paper deals with a nonlinear second-order one-dimensional evolutionary equation related to applications and describes various diffusion, filtration, convection, and other processes.
Alexander Kazakov, Anna Lempert
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source