Results 81 to 90 of about 6,117,968 (304)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Power Sharing in an Islanded Microgrid without Synchronous Generators

open access: yes, 2019
This paper addresses a power sharing method of electronically interfaced distributed generation (DG) units in the context of a multiple-DG microgrid system where there is no synchronous generator. The emphasis is primarily on electronically interfaced DG
Mohammad Alomgir Hossain   +5 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Political Power Sharing and Crosscutting Media Exposure: How Institutional Features Affect Exposure to Different Views

open access: yesInternational Journal of Communication, 2020
Previous research shows that power-sharing political systems are associated with (a) individual perceptions of political inclusiveness and (b) a more deliberative news media supply. Little, however, is known about the effect of this institutional feature
Laia Castro, Lilach Nir
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Why Northern Ireland’s Institutions Need Reform

open access: yesGovernment and Opposition
In a previous volume of this journal, scholars of consociational power-sharing counselled against reform of Northern Ireland’s power-sharing institutions.
Sean Haughey, Jon Tonge, Ben Rosher
doaj   +1 more source

Power Flow Control Strategy Based on the Voltage Vector Distribution for a Dual Power Electric Vehicle With an Open-End Winding Motor Drive System

open access: yesIEEE Access, 2018
A dual inverter feeding an open-end winding permanent magnet synchronous motor drive system can realize controllable power sharing or power flow between two independent power sources without a dc/dc converter.
Yi-Fan Jia   +6 more
doaj   +1 more source

Participation in the Sharing Economy [PDF]

open access: yes, 2017
Report from the EU H2020 Research Project Ps2Share: Participation, Privacy, and Power in the Sharing EconomyLiterature ...
Anselmi, Guido   +4 more
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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