Results 91 to 100 of about 286,515 (301)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

AC fault ride-through control strategy of MMC-UHVDC system with hierarchical connection mode

open access: yesFrontiers in Energy Research
The ultra-high voltage direct current (UHVDC) transmission composed of modular multilevel converters (MMC) is an important technology for large-scale centralized transmission of renewable energy.
Mingli Ping   +5 more
doaj   +1 more source

Sensors and Fault Diagnostics in Power System

open access: yesSensors
The adequate technical condition assessment of key apparatuses is a crucial assumption in the delivery of reliable and continuous electric power to customers [...]
Michał Kunicki   +2 more
openaire   +3 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Modeling and Simulating Long-Timescale Cascading Faults in Power Systems Caused by Line-Galloping Events

open access: yesEnergies, 2017
With the increasing occurrence of extreme weather events, the short circuit and line-breaking faults in transmission lines caused by line galloping have been threatening the security operation of power systems.
Lizheng Chen   +3 more
doaj   +1 more source

Protection challenges in future converter dominated power systems [PDF]

open access: yes, 2015
Converter interfaces, used to connect renewable energy sources, HVDC links and infeeds to the power system, will bring significant changes to the behaviour of power systems in the future, particularly in Great Britain (GB).
Booth, Campbell   +5 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Investigation of Failures during Commissioning and Operation in Photovoltaic Power Systems

open access: yesApplied Sciences
Considering global warming and environmental problems, the importance of renewable energy sources is increasing day by day. In particular, the effects of wind and solar power, which are variable renewable power sources, on the power system necessitate ...
Metin Gökgöz   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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