Advanced Healthcare Materials, EarlyView.Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Research on the impact mechanism of comprehensive land consolidation on rural human settlement environment based on the production-living-ecological space theory: a case study of Zhejiang Province, China. [PDF]
Front Public HealthMeng L, Yan F.
europepmc +1 more source
3D Printing Strategies for Bioengineering Human Cornea
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan +4 more
wiley +1 more source
An 18-Month Randomized Controlled Clinical Trial Evaluating the Clinical Success of IPS e.max Conventional Crowns and Endocrowns in Extensively Restored Molars. [PDF]
Clin Exp Dent ResDalol RE, Abou Nassar JN, Hajeer MY.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji +8 more
wiley +1 more source
Clinical performance of single shade universal resin composites: a randomized controlled one year follow-up study. [PDF]
BMC Oral HealthÇadırcı M, Özakar N.
europepmc +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Multi-modal low-dose medical imaging through instruction-guided unified AI. [PDF]
Front Med (Lausanne)Lang H +10 more
europepmc +1 more source
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
Advanced Healthcare Materials, EarlyView.A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
Decoding Biodiversity in Baiyangdian Lake: A DNA Barcode Reference Library for Aquatic Insects. [PDF]
InsectsQiao YJ +8 more
europepmc +1 more source